Active pharmaceutical ingredients (APIs) could be combined at the point of care, allowing for customized therapies. Developing, marketing, and pricing these curative treatments could require the biopharma sector to adopt new capabilities. Considerations: These technologies could be highly disruptive to biopharmaceutical companies by eliminating the need for drug therapy. View in article, National Institutes of Health, “Researchers develop microneedle patch for flu vaccination,” June 27, 2017. In October 2019, Telangana Government proposed Hyderabad Pharma City with financial assistance from the Central government of Rs 3,418 crore (US$ 489 million). View in article, Philip D. Greenberg, “How cellular immunotherapies are changing the outlook for cancer patients,” Cancer Research Institute, accessed February 25, 2020. The changes that we see on the horizon will likely require biopharma companies to consider new types of markets, alternative business models, or a complete change in how they define what work they do. The engineered tissue develops a circulatory system, secretes hormones such as insulin, and has successfully treated sudden-onset Type 1 diabetes in mice.27. We define a customized treatment as a single therapy, or mix of therapies, that is selected, tailored, or developed to treat an individual. Advanced cognitive technologies could be developed to analyze a significantly large set of parameters and create personalized insights into a consumer’s health. Non-negotiable, however, is that these technologies need to demonstrate results. With the benefits and detriments of pharmaceuticals well-documented, one question remains: where does Pharma go from here? Using cognitive and behavioral therapy techniques to address sleep disorders, the app strives to be entertaining as well as tailored to each user. Precision intervention: Increasingly sophisticated medical technology—such as precise medical intervention enabled by robotics, nanotechnology, or tissue engineering—could reduce the need for pharmaceutical intervention. View in article, U.S. Food & Drug Administration, “Gardasil vaccine safety,” April 20, 2009. 7 (2018). By 2040 (and perhaps beginning much before), streams of health data—together with data from a variety of other relevant sources—will likely merge to create a multifaceted and highly personalized picture of every consumer’s well-being. What are some examples of disruption already happening in the market, and how quickly is change likely to occur? Lastly, companies might need to explore novel financing mechanisms to enable both access and affordability given that the short-duration treatment has the potential for a life time of benefit. Anecdotal stories on MyMee’s website highlight individuals who were able to learn about and understand the triggers that are negatively impacting their bodies. Exclusive market research and insights from leading thought leaders on the front lines of their industry. There will be increased attention to cost and abrupt cost increases. Comprehensive audit, advisory, consulting, and tax capabilities can deliver value at every step, from insight to strategy to action. A future marked by greater access to needed Systematic evaluation of how patients metabolize drugs by evaluating the expression of liver enzymes (CYP450) or kidney function could enable more optimal dosing to get patients into therapeutic ranges. Biopharma companies working in impacted disease areas should consider adopting some of these technologies, or risk operating in a much smaller market in the future. Cell Therapy is the transfer of live cells into a patient to help lessen or cure a disease. Growth is driven by increased contribution from orphan drugs as they will grow to 20% of the prescription drug market. Copy a customized link that shows your highlighted text. We are already seeing advancements in the ability to detect the early stages of cancer. It’s actually a set of discrete diseases, and some variations of Parkinson’s look different than others. A therapy that is effective for one patient, might be metabolized differently by another patient and never reach the optimal active concentration, he noted. “At present, large pharma companies develop medicines in two principal ways. 1 (2019): pp. By 2030, we should not simply expect more targeted therapies, practitioners will also be able to predict the likelihood of a patient being diagnosed with a disease or health condition, and shift from treatment of … This includes advances in robotic surgery, nanotechnology, and tissue engineering. shrikant.py2011@gmail.com INTRODUCTION: The Pharmaceutical industry in India is the world's third-largest in terms of volume and stands 14th in terms of value. Most could benefit from developing a business model that focuses on more customized treatments. One interviewee suggested that the adoption of health care apps will likely reach a tipping point once major health systems, health plans, and large pharmacies “prioritize digital therapeutics over prescriptions and pay for them.”, Sleepio: Sleepio, a digital sleep improvement program, was founded in 2010. Search for more papers by this author. “I would summarize that the future of pharma is in continued development in immuno-oncology and non-opioid pain therapy. The pharmaceutical industry, once dominated by R&D-driven growth and by aggressive marketing to deliver high margins, is now under pressure and subject to considerable change. It aims to close gaps in care, provide refill deliveries, and personalize care through both its digital offering and access to real-time health specialists and coaches. The vast majority of patients may not receive the full potential benefit of drugs that they are treated with because we don’t yet know how to effectively stratify patient populations, one interviewee noted. Researchers from the Deloitte Center for Health Solutions interviewed 14 thought leaders (futurists, venture capitalists, digital health leaders, and academics) to find out how they expected the identification, prevention, and treatment of disease to evolve between now and 2040. Unlike some high-cost therapies that treat a small portion of the population, the generic-drug business model is based entirely on high-volume treatments that target large populations. Stratifying disease to target the best drug intervention: Advances in the understanding of biomarkers and genetic markers have helped researchers identify subpopulations within broader disease categories. AI might be used to spot biomarkers that would indicate a potential change in health status before symptoms appear. Two other examples of virally transfused cancers include the human T-lymphotropic virus type 3 (HTLV-3) and the hepatitis B and C viruses, which can cause liver cancer. Pharmaceutical companies that are able to reimagine their traditional business model may be most likely to succeed in a future built around prevention, early detection, and personalized therapies. View in article, Business Wire, “Global human microbiome market analysis & forecast, 2020—The market was valued at USD 351.81 million in 2018,” February 6, 2020. Biopharma companies should consider the potential for disruption by these forces as they redefine the types of products and solutions they will offer, where they will compete, and the new capabilities they will require. But medicine can always be better, and the pharmaceutical branch of the healthcare industry plays a bigger role than ever in our everyday lives. Since the outbreak, retail of over-the-counter drugs spiked before lockdowns in March 2020 as consumers stockpiled these drugs. She conducts primary and secondary research and analysis on emerging trends, challenges, and opportunities within the health care system. By 2050, there will be two billion people that are 60 years or older globally. Future Prospects. View in article, Beth A. Helmink et al., “The microbiome, cancer, and cancer therapy,” Nature Medicine 25 (2019): pp. Researchers at the University of Vermont and Tufts University have designed organic robots by joining together specific types of stem cells taken from a well-studied species of African frog, Xenopus laevis. While these too are vaccines, they bear no resemblance to vaccines that prevent an infectious agent. Companies who run from one quarterly financial report to the next, ignoring the future, will not survive. Further, additive manufacturing could lead to new ways of delivering drugs. 377–88. It allows users to input and track their daily activities, and then make sense of any patterns in the data that might be impacting their health. The way individuals express disease and respond to treatment varies greatly. In response, they were able to change their diets and lifestyle habits to avoid those triggers. Giving each patient a personalized dosage, or the optimal combination of drugs, could lead to better outcomes. The company said it detected strong signals for 12 cancers with a 99 percent specificity rate.6, Nutrition and microbiome: Everyone has a unique microbiome, and researchers are just beginning to understand the relationship between these tiny organisms and how they influence mental and physical health. We expect that over the next 20 years, we will be able to detect some diseases—and prevent them from advancing—possibly even before symptoms surface. 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